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Abiraterone acetate for prostate cancer with

Basic Info

Model No.: YH-P-5

Product Description

Abiraterone acetate ,used for prostatic cancer,Abiraterone acetate is approved to be used with prednisone to treat Prostate cancer that has metastasized (spread to Other parts of the body). It is used in patients whose disease has not gotten better with other hormone therapy.
Storage: Keep in sealed and damp proof place.

Factory supply high quality Abiraterone Acetate with reasonable price and fast delivery on hot CAS 154229-18-2

1. Chemical Data
CAS No: 154229-18-2
Synonyms: 17-(3-pyridyl)-5,16-androstadien-3beta-acetate; CB 7630;
(3)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol Acetate (Ester);
Molecular Formular: C26H33NO2
Molecula Weight: 391.5457
Appearance: White or off-white solid

2. Chemical Specification
Purity(HPLC): 99% min
NMR: Complies
Assay(HPLC): 98.0-102% (Calculated on dry basis)
Tetrahydrofuran: <720ppm
Methanol: <0.3%
Ethanol: <0.5%
Pyridine: <200ppm
Isopropanol: <0.5%
Acetic acid: <0.5%
Melting point: 143-149℃
Related substances: <0.5%
Individual impurity: <0.1%
Loss on drying: <1.0%
Residue on ignition: <0.2%
Particle size: 100%<50um

3. Abiraterone Acetate

Treating a certain type of prostate cancer that has spread to other parts of the body. It is used along with another medicine (prednisone). It may also be used for other conditions as determined by your doctor.

Abiraterone acetate is an androgen biosynthesis inhibitor. It works by decreasing levels of certain hormones produced by the testes. This helps to prevent the growth of certain tumors that need these hormones to grow.

4. Do NOT use abiraterone acetate if:
you are allergic to any ingredient in abiraterone acetate
you have severe liver problems
you are pregnant or may become pregnant

Contact your doctor or health care provider right away if any of these apply to you.

5. Before using abiraterone acetate:

Some medical conditions may interact with abiraterone acetate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of liver problems, heart problems (eg, heart failure, irregular heartbeat), a recent heart attack, or high blood pressure
if you have low blood potassium levels or a history of adrenal gland problems, pituitary gland problems, or fluid retention or swelling (edema)

Some MEDICINES MAY INTERACT with abiraterone acetate. Tell your health care provider if you are taking any other medicines, especially any of the following:
Atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, or voriconazole because they may increase the risk of abiraterone acetate's side effects
Carbamazepine, phenobarbital, phenytoin, rifabutin, rifampin, or rifapentine because they may decrease abiraterone acetate's effectiveness
Carvedilol, chlorpromazine, desipramine, dextromethorphan, encainide, flecainide, iloperidone, maprotiline, metoprolol, nortriptyline, paroxetine, pimozide, propafenone, propranolol, risperidone, tetrabenazine, or thioridazine because the risk of their side effects may be increased by abiraterone acetate

Abiraterone Acetate

Chemical Data

CAS No

154229-18-2

Synonyms

17-(3-pyridyl)-5,16-androstadien-3beta-acetate; CB 7630;

(3)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol Acetate (Ester);

Molecular Formular

C26H33NO2

Molecula Weight

391.5457

EINECS NO

Appearance

White or off-white solid

Packing

1kg Aluminium foil bag or as per client`s request

Uses

API ,used for prostatic cancer

Storage

Keep in sealed and damp proof place.

Chemical Specification

Purity(HPLC)

99% min

NMR

Complies

Assay(HPLC)

98.0-102% (Calculated on dry basis)

Tetrahydrofuran

<720ppm

Methanol

<0.3%

Ethanol

<0.5%

Pyridine

<200ppm

Isopropanol

<0.5%

Acetic Acid

<0.5%

Melting point

143-149

Related substances

<0.5%

Individual impurity

<0.1%

Loss on drying

<1.0%

Residue on ignition

<0.2%

Particle size

100%<50um

Conclusion

Conform to IN-HOUSE


6.Packing: 1kg Aluminium foil bag or as per client`s request

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